2-Chloro-5-nitropyridine (CAS 4548-45-2) is a highly reactive heteroaromatic compound widely used as an intermediate in pharmaceutical, agrochemical, and fine chemical synthesis. It contains both a chloro substituent and a nitro group on the pyridine ring, which allows for versatile chemical transformations.
Chemical Characteristics
This compound appears as a yellow to light brown crystalline solid. It is moderately soluble in organic solvents such as ethanol, acetone, and dichloromethane. The electron-withdrawing nitro group and the reactive chloro group make 2-chloro-5-nitropyridine suitable for nucleophilic substitution, reduction, and cross-coupling reactions.
Applications
Pharmaceutical Industry: Used as an intermediate in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds targeting antibacterial, antiviral, and anticancer properties.
Agrochemicals: Serves as a building block in the production of herbicides, fungicides, and other crop protection chemicals.
Organic Synthesis: Utilized in the preparation of heterocyclic compounds, functionalized pyridines, and specialty chemicals.
Its high reactivity enables efficient incorporation into larger molecular frameworks, making it a valuable reagent for medicinal chemistry and fine chemical research.
Research and Industrial Value
2-Chloro-5-nitropyridine is prized for its stability under standard storage conditions and predictable reactivity, which ensures consistent results in laboratory and industrial-scale syntheses. It is suitable for method development, pilot-scale production, and large-scale manufacturing.
Supply Information
UCHEM can supply 2-chloro-5-nitropyridine (CAS 4548-45-2) with high purity and stable stock. Bulk quantities are available for rapid delivery to support R&D, industrial synthesis, and large-scale production needs. Technical documents including COA and MSDS can be provided upon request.
