2-Chloro-5-nitropyridine (CAS 4548-45-2): Pyridine Intermediate with Large Stock Availability

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Author : Nina He
Update time : 2026-05-27 17:47:09

2-Chloro-5-nitropyridine CAS:4548-45-2 is a versatile pyridine-based intermediate widely used in pharmaceutical synthesis, agrochemical development, and heterocyclic chemistry. Featuring both chloro and nitro functional groups on the pyridine ring, this compound provides high reactivity for a variety of substitution and transformation reactions.

 

The chlorine atom enables efficient nucleophilic substitution, while the nitro group serves as an important functional handle for reduction, coupling, and further derivatization. Because of this balanced reactivity, 2-Chloro-5-nitropyridine is frequently used in the synthesis of active pharmaceutical ingredients (APIs), crop protection compounds, and specialty heterocyclic intermediates.

 

In medicinal chemistry, pyridine derivatives containing halogen and nitro substituents are often selected for scaffold construction and structure optimization due to their favorable electronic properties. This compound is also useful in multi-step synthesis routes requiring selective functionalization of nitrogen-containing aromatic systems.

 

With increasing demand for pyridine intermediates in fine chemical and pharmaceutical industries, stable supply of key building blocks has become especially important for production planning and project continuity.

 

UCHEM can provide large stock availability of 2-Chloro-5-nitropyridine CAS:4548-45-2, supporting fast delivery and scalable procurement needs for both research and industrial applications.

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