2,5-Dibromothiophene-3-carboxylic acid (CAS: 7311-70-8) - An Ideal Intermediate for Functionalized Thiophene Compounds

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Author : Nina He
Update time : 2025-09-24 17:27:13

2,5-Dibromothiophene-3-carboxylic acid is an important thiophene derivative featuring a carboxyl group and two bromine substituents, which provide high reactivity and great synthetic potential. Typically obtained as a light-colored solid, this compound shows both chemical stability and selectivity, making it an indispensable intermediate in research and industrial applications.

 

Structure and Reactivity

Dibromo substituents: Under Pd-catalyzed conditions, they participate in Suzuki, Stille, and other cross-coupling reactions to build multi-substituted thiophenes.

 

Carboxyl functionality: Suitable for condensation, esterification, or acyl chloride formation, offering access to diverse derivatives.

 

Multi-site modification: The combination of bromine atoms and a carboxyl group within one molecule allows sequential modifications, providing exceptional flexibility in complex synthesis.

 

Application Fields

Pharmaceutical synthesis: Serves as a key intermediate for thiophene-containing drug candidates.

 

Materials science: Plays an essential role in organic electronics, OLEDs, and organic field-effect transistors (OFETs).

 

Functional monomers: Enables the development of novel polymers and optoelectronic molecules through structural modification.

 

UCHEM Supply Advantage

UCHEM supplies high-purity 2,5-Dibromothiophene-3-carboxylic acid (CAS: 7311-70-8) with ready stock for fast delivery. We ensure strict quality control, flexible packaging, and technical support, helping customers accelerate research and production.

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