3-(Trifluoromethyl)phenol (CAS 98-17-9) is an important fluorinated aromatic compound widely used as an intermediate in pharmaceutical, agrochemical, and specialty chemical synthesis. Featuring a phenolic hydroxyl group and a trifluoromethyl substituent, this molecule exhibits enhanced chemical stability and unique electronic properties, making it valuable in modern organic synthesis.
This compound is typically a clear to light yellow liquid with a molecular formula of C7H5F3O and a molecular weight of 162.11. It has a boiling point of approximately 178–179°C and is insoluble in water but soluble in most organic solvents. The presence of the electron-withdrawing trifluoromethyl group significantly influences its reactivity, making it suitable for various substitution and coupling reactions.
Applications
Pharmaceutical Industry
3-(Trifluoromethyl)phenol is widely used as a key intermediate in the synthesis of active pharmaceutical ingredients, including fluorinated drug molecules. It has been utilized in the preparation of compounds such as prostaglandin analogs for therapeutic applications.
Agrochemical Synthesis
The compound serves as a building block for pesticides, herbicides, and fungicides, where fluorinated aromatic structures enhance bioactivity and environmental stability.
Dye and Material Chemistry
It is also applied in the synthesis of dyes, specialty materials, and functional polymers due to its stable aromatic structure and reactivity.
Supply Advantage
This product is available with hundreds of kilograms in stock, ensuring fast delivery and reliable supply for both research and industrial-scale applications. Consistent quality and stable production make it suitable for long-term procurement needs.
