5-Bromopyrimidine (CAS 4595-59-9) is a highly востребован heterocyclic intermediate widely used in pharmaceutical, agrochemical, and fine chemical synthesis. Owing to its versatile reactivity and electron-deficient pyrimidine core, this compound serves as a key building block for the development of numerous biologically active molecules and advanced functional materials.
5-Bromopyrimidine typically appears as an off-white crystalline powder with excellent solubility in polar organic solvents. The bromine atom at the 5-position provides a convenient reactive site for further derivatization through nucleophilic substitution and transition-metal-catalyzed cross-coupling reactions, including Suzuki, Sonogashira, Buchwald–Hartwig, and Stille coupling.
Applications
Pharmaceutical Intermediates
The pyrimidine scaffold is a common structural motif in many active pharmaceutical ingredients. 5-Bromopyrimidine is frequently used in the synthesis of kinase inhibitors, antiviral agents, and other therapeutic compounds.
Agrochemical Development
This compound serves as an important precursor for the preparation of herbicides, fungicides, and other crop protection products.
Fine Chemicals and Research
5-Bromopyrimidine is widely employed in medicinal chemistry, heterocyclic synthesis, and material science research, enabling the rapid construction of diverse pyrimidine derivatives.
In addition to 5-Bromopyrimidine, UCHEM also supplies the following pyrimidine intermediates:
2-Chloropyrimidine (CAS 1722-12-9)
2-Bromopyrimidine (CAS 4595-60-2)
2-Cyanopyrimidine (CAS 14080-23-0)
These products provide complementary reactivity for various synthetic routes and support a wide range of pharmaceutical and agrochemical applications.
Supply Advantage
UCHEM maintains ready stock for all of the above products, ensuring fast delivery and reliable supply. With stringent quality control, stable inventory management, and flexible packaging options, we support both research-scale projects and commercial manufacturing requirements.
