Boc-Arg(NO2)-OH CAS 2188-18-3 for Solid-Phase Peptide Synthesis

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Author : Nina He
Update time : 2026-08-11 17:51:32

Boc-Arg(NO2)-OH (CAS 2188-18-3) is a valuable protected arginine derivative widely used as an amino acid building block in peptide chemistry. With a molecular weight of 319.31 g/mol, this compound is designed to provide controlled reactivity during multistep peptide assembly while protecting functional groups that could otherwise interfere with synthesis.

 

The Boc (tert-butoxycarbonyl) group protects the α-amino functionality, while the nitro group serves as a protecting group for the guanidino side chain of arginine. This orthogonal protection strategy makes Boc-Arg(NO2)-OH particularly useful in controlled peptide assembly and solid-phase peptide synthesis (SPPS).

 

During peptide synthesis, protected amino acid derivatives such as Boc-Arg(NO2)-OH help minimize undesired side reactions and enable selective formation of peptide bonds. It can therefore be incorporated into research workflows involving synthetic peptides, peptide analogues, bioactive sequences, and structure–activity relationship studies.

 

Boc-Arg(NO2)-OH is suitable for applications in pharmaceutical research, medicinal chemistry, peptide drug development, and biochemical research. Its defined protection pattern makes it a practical building block for laboratories requiring reproducible peptide synthesis and downstream deprotection strategies.

 

UCHEM supplies Boc-Arg(NO2)-OH CAS 2188-18-3 with strict quality control and consistent batch performance. We support customers engaged in peptide research and pharmaceutical development with reliable supply, flexible quantities, and professional technical service.

 

With experience in amino acid derivatives and peptide synthesis intermediates, UCHEM provides high-quality building blocks for research institutions, biotechnology companies, and pharmaceutical manufacturers worldwide.

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