Ethyl 2-Butynoate (CAS 4341-76-8): Applications in Organic Synthesis and Methanogenesis Inhibition

Author : Nina He

Update time : 2025-05-15 17:55:01

Ethyl 2-butynoate cas:4341-76-8, also known as ethyl tetrolate, is an electron-deficient alkyne ester with a molecular weight of 112.13 g/mol .

Key applications include:

Precursor in synthesizing tricyclic aziridines, alkenylsilanols, and cyclopentene dicarboxylates .

Methanogenesis inhibitor and key reagent in Rh(I)/H8-BINAP-catalyzed 1,3-diene preparations .

Intermediate in stereoretentive cross-coupling reactions and total syntheses of natural products like waixenicin A .

Ethyl 2-butynoate cas:4341-76-8, a 2-alkynoate is a methanogenesis inhibitor. It is an electron deficient internal alkyne that has been reported to undergo codimerization with alkenes to form 1,3-dienes catalyzed by rhodium(I)/H8-BINAP complex.

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Ethyl 2-Butynoate (CAS 4341-76-8): Applications in Organic Synthesis and Methanogenesis Inhibition