Myristoyl-Gly-OH (N-Myristoylglycine) CAS: 14246-55-0 is a lipidated amino acid derived from glycine, where a myristoyl (tetradecanoyl) group is covalently attached to the amino terminus. Key properties include:
Synonyms: N-Tetradecanoylglycine
Molecular Formula: C16H31NO3
Molecular Weight: 285.42 g/mol
This compound is part of the N-acylglycine family, characterized by their roles in lipid metabolism and signaling.
Chemistry
Myristoyl-Gly-OH is often used as a model compound to study lipidation mechanisms and amide bond formation. It provides a reference framework for synthesizing other lipidated amino acids and peptides, aiding the understanding of lipid modifications in proteins.
Biology
Biologically, this compound participates in cellular processes such as membrane targeting and protein-protein interactions. As a product of protein myristoylation, it influences protein localization, stability, and function, thereby playing a key role in signal transduction pathways.
Medicine
In medical research, Myristoyl-Gly-OH shows potential therapeutic value. It has been reported to induce browning of adipocytes, which may contribute to obesity management and metabolic regulation by promoting brown adipose tissue differentiation.
Industry
In industrial applications, it is valued in cosmetics and personal care formulations for its emollient properties. It improves product texture and stability, making it a useful additive in skincare and cosmetic products.
