Phenyl-pyrrolidin-1-yl-acetic acid CAS 100390-48-5 : A Versatile Intermediate for Drug Research

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Author : Nina He
Update time : 2026-01-23 17:13:11

Phenyl-pyrrolidin-1-yl-acetic acid (CAS: 100390-48-5) is a valuable organic intermediate featuring both a phenyl group and a pyrrolidine moiety, which together impart favorable chemical reactivity and biological relevance. Owing to its well-defined structure, this compound is widely applied in pharmaceutical research, medicinal chemistry, and fine chemical synthesis.

 

In organic and medicinal chemistry, Phenyl-pyrrolidin-1-yl-acetic acid serves as an important building block for the synthesis of bioactive molecules. The pyrrolidine ring is a common pharmacophore found in numerous drug candidates, while the phenyl group enhances molecular interactions such as π-π stacking and hydrophobic binding. As a result, derivatives based on this scaffold are frequently investigated for central nervous system (CNS) activity, enzyme inhibition, and receptor modulation.

 

In pharmaceutical R&D, this compound is used as an intermediate in the development of small-molecule drugs and lead compounds. Its carboxylic acid functionality allows convenient derivatization into esters, amides, or salts, enabling structure–activity relationship (SAR) studies and optimization of physicochemical properties.

 

From an industrial perspective, Phenyl-pyrrolidin-1-yl-acetic acid is also applied in the preparation of specialty chemicals and advanced intermediates, supporting scalable synthesis routes for high-value products.

 

UCHEM can supply Phenyl-pyrrolidin-1-yl-acetic acid (CAS: 100390-48-5) with reliable quality and stable availability, suitable for laboratory research as well as larger-scale production requirements.

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