(R,R)-(+)-2,2'-Isopropylidenebis(4-tert-butyl-2-oxazoline) CAS:131833-97-1 is a widely recognized chiral bisoxazoline ligand commonly used in asymmetric catalysis and enantioselective synthesis. As part of the BOX (bisoxazoline) ligand family, this compound plays a critical role in modern catalytic chemistry due to its excellent stereochemical control and coordination ability with transition metals.
The molecular structure features two oxazoline rings connected through an isopropylidene bridge and substituted with tert-butyl groups, providing both steric and electronic effects that enhance catalytic selectivity. These structural characteristics allow the ligand to form stable metal complexes with copper, zinc, and other transition metals, which are widely used in enantioselective transformations such as cyclopropanation, Diels–Alder reactions, and allylic oxidation.
Because of its ability to induce high enantioselectivity, (R,R)-(+)-2,2'-Isopropylidenebis(4-tert-butyl-2-oxazoline) has become an important tool in pharmaceutical synthesis, natural product synthesis, and advanced organic chemistry research. It is frequently utilized in catalytic systems designed for the efficient preparation of chiral molecules and active pharmaceutical intermediates.
UCHEM supplies high-purity (R,R)-(+)-2,2'-Isopropylidenebis(4-tert-butyl-2-oxazoline) with strict quality control and reliable batch consistency. Our supply capabilities support research institutions, chemical manufacturers, and pharmaceutical development laboratories with flexible quantities and customized production solutions.
With strong expertise in chiral ligands and fine chemical intermediates, UCHEM is committed to providing reliable materials that support innovation in asymmetric synthesis and catalytic chemistry.
