1-Bromododecane CAS 143-15-7: Versatile Alkylation Reagent for Specialty Chemicals and Functional Materials

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Author : Nina He
Update time : 2026-10-22 17:54:30

1-Bromododecane CAS:143-15-7 is a linear primary bromoalkane with the molecular formula C12H25Br and a molecular weight of 249.23 g/mol. Featuring a twelve-carbon alkyl chain and a reactive bromine group, this compound is an important organic synthesis intermediate used in alkylation reactions, specialty chemical manufacturing, and functional material development.

 

The bromine atom enables nucleophilic substitution reactions, allowing the dodecyl group to be introduced into suitable molecular structures. This makes 1-Bromododecane useful for modifying molecular properties such as hydrophobicity, lipophilicity, and compatibility with different solvents or polymer matrices.

 

Key Applications of 1-Bromododecane

1. Quaternary Ammonium Compounds and Ionic Liquids

1-Bromododecane is used in the synthesis of dodecyl-substituted quaternary ammonium compounds and related specialty chemicals. The long alkyl chain can contribute hydrophobic character and surface-active properties, making these derivatives relevant to surfactants, phase-transfer catalysts, and selected ionic liquid systems.

 

2. Functional Polymer Modification

In polymer chemistry, 1-Bromododecane can serve as an alkylating reagent for introducing long-chain hydrophobic groups into suitable functional polymers. Such modifications can influence water affinity, interfacial behavior, and compatibility with other formulation components. Applications include research involving ethoxylated urethanes, polyurethanes, and other polymeric materials.

 

3. Organic Electronics and Molecular Solubility

The introduction of long alkyl chains is a common strategy for modifying the solubility and solution processability of organic compounds. In research involving rigid polycyclic aromatic hydrocarbons and organic electronic materials, alkylation can help improve compatibility with selected organic solvents and facilitate solution-based processing. 1-Bromododecane provides a useful starting material for developing such alkylated derivatives.

 

4. Lipophilicity Modification in Organic and Biological Research

Attaching a dodecyl group can increase the hydrophobic character of suitable molecules. This approach is relevant to the preparation of compounds with tailored partitioning behavior, membrane interactions, or compatibility with lipid-rich environments. The resulting properties depend on the molecular scaffold and the specific substitution pattern.

 

With its reactive primary bromide functionality and linear C12 alkyl chain, 1-Bromododecane CAS:143-15-7 is a versatile building block for organic synthesis, quaternary ammonium chemistry, polymer modification, and specialty material development.

 

UCHEM supplies 1-Bromododecane for research and industrial synthesis applications. Contact us for product specifications, availability, packaging options, and supply requirements.

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