3-Chloro-2-hydroxy-1-propanesulfonic Acid Sodium Salt Hydrate CAS 143218-48-8 - Anionic Modifier for Surface Functionalization

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Author : Nina He
Update time : 2026-06-17 17:14:48

3-Chloro-2-hydroxy-1-propanesulfonic acid sodium salt hydrate (CAS 143218-48-8) is a versatile anionic reagent widely used in surface modification, cellulose functionalization, and materials science research. Featuring both a reactive chlorohydrin group and a sulfonate functionality, this compound enables the introduction of stable negative charges onto a variety of substrates.

 

As a novel anionic agent, it is particularly valuable for tailoring surface properties, controlling zeta potential, and studying interactions between charged materials.

 

Chemical Characteristics

3-Chloro-2-hydroxy-1-propanesulfonic acid sodium salt hydrate typically appears as a white to off-white crystalline powder with good water solubility. The chlorohydrin group readily reacts with hydroxyl-containing materials, while the sulfonate moiety imparts permanent anionic character.

 

This unique combination of reactivity and charge functionality makes it an effective reagent for preparing negatively charged surfaces and functional materials.

 

Applications

Cellulose Surface Modification

The compound is widely used to functionalize cellulose fibers and microcrystalline cellulose (MCC), introducing sulfonate groups that enhance surface charge and dispersibility.

 

Probe Particle Preparation

It has been employed in the preparation of negatively charged probe particles to investigate the influence of nanoporosity in cellulosic fibers on streaming potential and interactions with cationic polyelectrolytes.

 

Zeta Potential Control

3-Chloro-2-hydroxy-1-propanesulfonic acid sodium salt hydrate is used to prepare surface-derivatized MCC particles with well-defined positive or negative zeta potentials, enabling studies of colloidal stability and interfacial behavior.

 

Materials Science Research

The reagent is valuable for developing functional materials, modifying polysaccharides, and investigating electrostatic interactions in dispersions, coatings, and composite systems.

 

Key Benefits

  • Efficient introduction of stable anionic functionality
  • Excellent water solubility
  • Suitable for cellulose and polysaccharide modification
  • Enables precise control of surface charge and zeta potential
  • Useful for colloidal and interfacial research

3-Chloro-2-hydroxy-1-propanesulfonic acid sodium salt hydrate (CAS 143218-48-8) is available with high purity and consistent quality for research and industrial applications.

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